IGSR Project Leader

Competitive Salary
26 Jul 2017
13 Aug 2017
Contract Type
Full Time
IGSR Project LeaderLocation:EMBL-EBI Hinxton near Cambridge, UK Staff Category:Staff memberContract Duration:until 31.08.2020Grading:6 or 7 (monthly salary starting at GBP2,856 or GBP3,250 after tax). For more information about pay and benefits click hereClosing Date:13 August 2017Reference Number:EBI_01005Job Description

EMBL-EBI seeks an enthusiastic project leader to head the efforts of the International Genome Sample Resource (IGSR).

The goal of IGSR is to create and maintain the largest fully open resource for the study of worldwide human genetic variation and its functional effects. IGSR provides support and updates for the existing resources of the 1000 Genomes Project and is actively extending the data collection with new populations and data type including transcriptiomic and regulatory data generated from populations with consent for full, open data release of genetic data. IGSR includes capacity for analysis, data coordination and ethics advice to participate as active collaborators in new data generation projects.

You will be responsible for managing the 3-4 person IGSR project group and will be expected to actively engage with collaborators and potential collaborating projects around the world, with the goal of expanding the scope of IGSR. Current active collaborative projects include participation in the Human Genome Structural Variation Consortium, the African Genome Variation Project and other related projects. We are targeting future engagement toward the creation of open references alongside national genome sequencing initiatives advancing in the context of the Global Alliance for Genomics and Health (GA4GH).

In addition to the management and engagement responsibilities, you will have oversight of the following IGSR activities:

  • Maintenance and updates to the IGSR web portal

  • Creation and running of computational pipelines relevant for variation data

  • Incorporation of relevant data from new technologies

  • Collaboration with other EMBL-EBI resources

  • Publications describing IGSR data sets and processes

Within EMBL-EBI, IGSR is part of the Genes, Genomes and Variation cluster of resources (led by Paul Flicek) and collaborates closely with the Ensembl project and the European Variation Archive.

EMBL-EBI is part of the European Molecular Biology Laboratory (EMBL) and it is a world-leading bioinformatics centre providing biological data to the scientific community with expertise in data storage, analysis and representation. EMBL-EBI provides freely available data from life science experiments, performs basic research in computational biology and offers an extensive user training programme, supporting researchers in academic and industry. We have close ties with both the University of Cambridge and the Wellcome Trust Sanger Institute.

Qualifications and Experience

The successful candidate will have:

  • PhD Degree in Population or Statistical Genetics, Bioinformatics or equivalent qualification/experience in Computational, Physical or Biological Sciences;

  • Significant experience with computational analysis of genetic variation data arising from high throughput sequencing technologies;

  • Familiarity with population or statistical genomics;

  • Experience in working in large scientific projects, especially in genomics, would be strongly preferred;

  • Previous management experience will be advantage, but is not required.

Engagement with existing and potential IGSR collaborators is a key aspect of the job. This will involve some worldwide travel and an understanding of the specific national or regional context of the data providers. The project leader will be expected to work closely with leaders of relevant related projects both internal and external to EMBL-EBI.

Experience with software development, computational pipelines and basic web technologies will be an advantage.


EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation.

We have an informal culture, international working environment and excellent professional development opportunities but one of the really amazing things about us is the concentration of technical and scientific expertise - something you probably won't find anywhere else.

If you've ever visited the campus you'll have experienced first-hand our friendly, collegial and supportive atmosphere, set in the beautiful Cambridgeshire countryside. Our staff also enjoy excellent sports facilities including a gym, a free shuttle bus, an on-site nursery, caf??s and restaurant and a library.

Application Instructions

To apply please submit a covering letter and CV, with two referees, through our online system.

Additional Information

Applications are welcome from all nationalities - visa information will be discussed in more depth with applicants selected for interview.

EMBL-EBI is committed to achieving gender balance and strongly encourages applications from women, who are currently under-represented at all levels. Appointment will be based on merit alone.

This position is limited to the contract duration specified.

Applications will close at 23:00 GMT on the date listed above.

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